Basu B. Multicomponent Synthesis. Bioactive Heterocycles 2024
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Textbook in PDF format Multicomponent synthesis may provide new and green routes for obtaining bioactive heterocycles. These methods produce less organic waste due to no longer removing solvent and other components between reaction steps. It can be applied to the synthesis of heterocycles with reactions such as the Biginelli reaction. This book explores the use of multi-component reactions for various heterocyclic structures with bioactivity. Discusses multicomponent synthesis as a method for producing bioactive heterocycles. Explores three-component synthesis of heterocycles, domino reactions, click reactions, magnetic nanocatalyzed reactions and more. Synthesis of aza-heterocycles via one-pot domino multicomponent reaction approach One-pot three-component selective annulation strategies for the synthesis of bioactive β-lactam, pyrrole, and pyridine scaffolds One-pot three-component synthesis of quinolines and some other selective six-membered heterocycles with biological importance Multicomponent synthesis of biologically prominent tetrahydrobenzoxanthenone derivatives One-pot five/four-component synthesis of structurally diverse bioactive quinoxaline-annulated spiroheterocycles through the in situ formation of 11H-indeno[1,2-b]quinoxalin-11-ones Multicomponent synthesis of biologically active quinazolinone derivatives Recent approaches toward the synthesis of 1,2,3-triazoles using multicomponent techniques Synthesis of various bioactive tetrazoles via one-pot multicomponent click reactions L-Proline and its derivatives catalyzed one-pot multicomponent synthesis of biologically promising N- and O-heterocycles Microwave-assisted solvent-free multicomponent synthesis of bioactive heterocycles Deep eutectic mixture (DEM)-assisted multicomponent synthesis of heterocycles