Textbook in PDF format

This book presents the ‘state of the art’ of biomarkers research in neuropsychiatric conditions, from dementia to eating disorders, as well as providing methodological, practical and ethical issues related to the development of biomarkers. Biomarkers have revolutionized clinical research and practice in most fields of medicine, but psychiatry has lagged behind. However, in the last decade, there has been a growing expectation that biomarkers will advance and, ultimately, reframe psychiatry research and practice. Biomarkers might inform about diagnosis, therapeutics, prognosis, contributing to a ‘personalized medicine’. Understanding their meaning, possibilities and limitations will help clinicians, researchers and students in the related areas navigate and excel in the challenging and ever changing field of neuropsychiatric disorders.
Biomarkers in Medicine and Psychiatry: An Overview
Genetic Biomarkers of Psychiatric Disorders
Findings in Specific Disorders
Clinical Applications of Genetic and Epigenetic Studies
Neurophysiological Biomarkers
Structural Neuroimaging Biomarkers in Psychiatry
Functional Neuroimaging Biomarkers
PET Biomarkers in Psychiatry
Digital Markers of Mental Health Problems: Phenotyping Across Biological, Psychological, and Environmental Dimensions
Staging Biomarkers in Psychiatry
Biomarkers of Delirium and Cognitive Impairment
Fluid-Based Biomarkers of Alzheimer’s Disease
Neuroimaging Biomarkers in Alzheimer’s Disease and Related Disorders
Biomarkers of Cognitive Decline and Dementia in Down Syndrome
Biomarkers of Schizophrenia
Biomarkers for Bipolar Disorder
Biomarkers in Anxiety Disorders
Biomarkers in Obsessive-Compulsive Spectrum Disorders
Sleep Disorders: Identifying Biomarkers and Clinical Applications
Biomarkers in Substance Use Disorder
Biomarkers of Traumatic Brain Injury and Related Neuropsychiatric Symptoms and Disorders
Biomarkers in Psychiatry: Conceptual and Methodological Challenges
Ethical Issues Related to Biomarkers in Psychiatry
Index